Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells,...
Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition
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Full title
Author / Creator
XU, KANG , CHEN, WEIJIAN , WANG, XIAOFEI , PENG, YAN , LIANG, ANJING , HUANG, DONGSHENG , LI, CHUNHAI and YE, WEI
Publisher
Athens: D.A. Spandidos
Journal title
Language
English
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Publication information
Publisher
Athens: D.A. Spandidos
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Scope and Contents
Contents
Proteoglycan degradation contributing to the pathogenesis of intervertebral disc (IVD) degeneration is induced by inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Cell autophagy exists in degenerative diseases, including osteoarthritis and inter-vertebral disc degeneration. However, the autophagy induced b...
Alternative Titles
Full title
Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4533778
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4533778
Other Identifiers
ISSN
1107-3756
E-ISSN
1791-244X
DOI
10.3892/ijmm.2015.2280
