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Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate...

Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4536571

Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate lymphoid cells

About this item

Full title

Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate lymphoid cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-08, Vol.6 (1), p.8010-8010, Article 8010

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Monocytes play a crucial role in antimicrobial host defence, but the mechanisms by which they protect the host during intestinal infection remains poorly understood. Here we show that depletion of CCR2
+
monocytes results in impaired clearance of the intestinal pathogen
Citrobacter rodentium
. After infection, the
de novo
recruite...

Alternative Titles

Full title

Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate lymphoid cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4536571

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4536571

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms9010

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