Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
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Author / Creator
Northcott, Paul A. , Hielscher, Thomas , Dubuc, Adrian , Mack, Stephen , Shih, David , Remke, Marc , Al-Halabi, Hani , Albrecht, Steffen , Jabado, Nada , Eberhart, Charles G. , Grajkowska, Wieslawa , Weiss, William A. , Clifford, Steven C. , Bouffet, Eric , Rutka, James T. , Korshunov, Andrey , Pfister, Stefan and Taylor, Michael D.
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Scope and Contents
Contents
Recent integrative genomic approaches have defined molecular subgroups of medulloblastoma that are genetically and clinically distinct. Sonic hedgehog (Shh) medulloblastomas account for one-third of all cases and comprise the majority of infant and adult medulloblastomas. To discern molecular heterogeneity among Shh-medulloblastomas, we analyzed tr...
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Full title
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4538327
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4538327
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-011-0846-7
