Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is suffi...
Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
About this item
Full title
Author / Creator
Li, P , Rial, D , Canas, P M , Yoo, J-H , Li, W , Zhou, X , Wang, Y , van Westen, G J P , Payen, M-P , Augusto, E , Gonçalves, N , Tomé, A R , Li, Z , Wu, Z , Hou, X , Zhou, Y , PIJzerman, Ad , Boyden, E S , Cunha, R A , Qu, J and Chen, J-F
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Human and animal studies have converged to suggest that caffeine consumption prevents memory deficits in aging and Alzheimer’s disease through the antagonism of adenosine A
2A
receptors (A
2A
Rs). To test if A
2A
R activation in the hippocampus is actually sufficient to impair memory function and to begin elucidating the intracell...
Alternative Titles
Full title
Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4539301
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4539301
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/mp.2014.182