On the primer binding site mutation that appears and disappears during HIV and SIV replication
On the primer binding site mutation that appears and disappears during HIV and SIV replication
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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A recent study by Fennessey et al. (Retrovirology 12:49, 2015) described the optimization of a popular SIV clone by removal of four suboptimal point mutations. One of these mutations is present in a non-coding part of the viral genome and is probed in that study in more detail because of some fascinating properties. This primer binding site (PBS) m...
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Full title
On the primer binding site mutation that appears and disappears during HIV and SIV replication
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4549124
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4549124
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ISSN
1742-4690
E-ISSN
1742-4690
DOI
10.1186/s12977-015-0201-5