Adaptive changes in the kinetochore architecture facilitate proper spindle assembly
Adaptive changes in the kinetochore architecture facilitate proper spindle assembly
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Mitotic spindle formation relies on the stochastic capture of microtubules at kinetochores. Kinetochore architecture affects the efficiency and fidelity of this process with large kinetochores expected to accelerate assembly at the expense of accuracy, and smaller kinetochores to suppress errors at the expense of efficiency. We demonstrate that on...
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Full title
Adaptive changes in the kinetochore architecture facilitate proper spindle assembly
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4553083
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4553083
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3223
