Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Sprouting angiogenesis drives blood vessel growth in healthy and diseased tissues. Vegf and Dll4/Notch signalling cooperate in a negative feedback loop that specifies endothelial tip and stalk cells to ensure adequate vessel branching and function. Current concepts posit that endothelial cells default to the tip-cell phenotype when Notch is inactiv...
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Full title
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4557308
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4557308
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms8264
