Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric sp...
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Bax is a key regulator of apoptosis that mediates the release of cytochrome c to the cytosol via oligomerization in the outer mitochondrial membrane before pore formation. However, the molecular mechanism of Bax assembly and regulation by other Bcl-2 members remains obscure. Here, by analysing the stoichiometry of Bax oligomers at the single-molecu...
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Full title
Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4557355
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4557355
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9042
