Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 tra...
Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Heat-shock response is an adaptive response to proteotoxic stresses including heat shock, and is regulated by heat-shock factor 1 (HSF1) in mammals. Proteotoxic stresses challenge all subcellular compartments including the mitochondria. Therefore, there must be close connections between mitochondrial signals and the activity of HSF1. Here, we show...
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Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4558571
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4558571
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7580
