Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblasto...
Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Aim： In the penumbra after focal cerebral ischemia, an increase of protease Omi is linked to a decrease of Hsl-associated protein X-1 （Hax-1）, a protein belonging to the Bcl-2 family. In this study we investigated the mechanisms underlying the regulation of Hax-1 by protease Omi in cerebral ischemia/reperfusion （I/R） injury. Methods： Mouse neurobla...
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Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4561969
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4561969
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ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2015.50
