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Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564017

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

About this item

Full title

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2014-10, Vol.16 (10), p.931-941

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The mechanism by which angiogenic endothelial cells break the physical barrier of the vascular basement membrane and consequently sprout to form new vessels in mature tissues is unclear. Here, we show that the angiogenic endothelium is characterized by the presence of functional podosome rosettes. These extracellular-matrix-degrading and adhesive s...

Alternative Titles

Full title

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564017

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564017

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3036

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