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Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function durin...

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function durin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4568972

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

About this item

Full title

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2015-10, Vol.14 (5), p.847-856

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Summary
Downregulation of insulin‐like growth factor (IGF) pathways prolongs lifespan in various species, including mammals. Still, the cellular mechanisms by which IGF signaling controls the aging trajectory of individual organs are largely unknown. Here, we asked whether suppression of IGF‐I receptor (IGF‐1R) in adult stem cells preserves long...

Alternative Titles

Full title

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4568972

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4568972

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726,1474-9728

DOI

10.1111/acel.12365

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