Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function durin...
Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Summary
Downregulation of insulin‐like growth factor (IGF) pathways prolongs lifespan in various species, including mammals. Still, the cellular mechanisms by which IGF signaling controls the aging trajectory of individual organs are largely unknown. Here, we asked whether suppression of IGF‐I receptor (IGF‐1R) in adult stem cells preserves long...
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Full title
Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4568972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4568972
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ISSN
1474-9718
E-ISSN
1474-9726,1474-9728
DOI
10.1111/acel.12365