A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism
A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Respiratory syncytial virus (RSV) causes acute lower respiratory tract infections and is the leading cause of infant hospitalizations. Recently, a promising vaccine antigen based on the RSV fusion protein (RSV F) stabilized in the native prefusion conformation has been described. Here we report alternative strategies to arrest RSV F in the prefusio...
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Full title
A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4569726
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4569726
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9143
