The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a muri...
The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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We designed OP3-4 (YCEIEFCYLIR), a cyclic peptide, to mimic the soluble osteoprotegerin (OPG), and was proven to bind to RANKL (receptor activator of NF-κB ligand), thereby inhibiting osteoclastogenesis. We recently found that another RANKL binding peptide, W9, could accelerate bone formation by affecting RANKL signaling in osteoblasts. We herein d...
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The inhibitory effects of a RANKL-binding peptide on articular and periarticular bone loss in a murine model of collagen-induced arthritis: a bone histomorphometric study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4570694
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4570694
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1478-6354
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1478-6362,1478-6354
DOI
10.1186/s13075-015-0753-8
