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The senescent methylome and its relationship with cancer, ageing and germline genetic variation in h...

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in h...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4574115

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

About this item

Full title

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Publisher

England: BioMed Central Ltd

Journal title

Genome Biology, 2015-09, Vol.16 (1), p.194-194, Article 194

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Cellular senescence is a stable arrest of proliferation and is considered a key component of processes associated with carcinogenesis and other ageing-related phenotypes. Here, we perform methylome analysis of actively dividing and deeply senescent normal human epithelial cells.
We identify senescence-associated differentially methylated positio...

Alternative Titles

Full title

The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4574115

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4574115

Other Identifiers

ISSN

1474-760X,1474-7596

E-ISSN

1474-760X

DOI

10.1186/s13059-015-0748-4

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