The senescent methylome and its relationship with cancer, ageing and germline genetic variation in h...
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Cellular senescence is a stable arrest of proliferation and is considered a key component of processes associated with carcinogenesis and other ageing-related phenotypes. Here, we perform methylome analysis of actively dividing and deeply senescent normal human epithelial cells.
We identify senescence-associated differentially methylated positio...
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Full title
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4574115
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4574115
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-015-0748-4