Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release a...
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
About this item
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Author / Creator
Ryu, Jae Kyu , Petersen, Mark A. , Murray, Sara G. , Baeten, Kim M. , Meyer-Franke, Anke , Chan, Justin P. , Vagena, Eirini , Bedard, Catherine , Machado, Michael R. , Coronado, Pamela E. Rios , Prod'homme, Thomas , Charo, Israel F. , Lassmann, Hans , Degen, Jay L. , Zamvil, Scott S. and Akassoglou, Katerina
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Autoimmunity and macrophage recruitment into the central nervous system (CNS) are critical determinants of neuroinflammatory diseases. However, the mechanisms that drive immunological responses targeted to the CNS remain largely unknown. Here we show that fibrinogen, a central blood coagulation protein deposited in the CNS after blood–brain barrier...
Alternative Titles
Full title
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4579523
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4579523
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9164
