Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine...
Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors
About this item
Full title
Author / Creator
Baburajeev, C. P. , Dhananjaya Mohan, Chakrabhavi , Ananda, Hanumappa , Rangappa, Shobith , Fuchs, Julian E. , Jagadish, Swamy , Sivaraman Siveen, Kodappully , Chinnathambi, Arunachalam , Ali Alharbi, Sulaiman , Zayed, M. E. , Zhang, Jingwen , Li, Feng , Sethi, Gautam , Girish, Kesturu S. , Bender, Andreas , Basappa and Rangappa, Kanchugarakoppal S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Condensed-bicyclic triazolo-thiadiazoles were synthesized
via
an efficient “green” catalyst strategy and identified as effective inhibitors of PTP1B
in vitro
. The lead compound, 6-(2-benzylphenyl)-3-phenyl-[1,2,4]triazolo[3][1,3,4]thiadiazole (BPTT) was most effective against human hepatoma cells, inhibits cell invasion and decreases n...
Alternative Titles
Full title
Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors
Authors, Artists and Contributors
Author / Creator
Dhananjaya Mohan, Chakrabhavi
Ananda, Hanumappa
Rangappa, Shobith
Fuchs, Julian E.
Jagadish, Swamy
Sivaraman Siveen, Kodappully
Chinnathambi, Arunachalam
Ali Alharbi, Sulaiman
Zayed, M. E.
Zhang, Jingwen
Li, Feng
Sethi, Gautam
Girish, Kesturu S.
Bender, Andreas
Basappa
Rangappa, Kanchugarakoppal S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585680
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep14195
