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Calreticulin is required for development of the cumulus oocyte complex and female fertility

Calreticulin is required for development of the cumulus oocyte complex and female fertility

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585710

Calreticulin is required for development of the cumulus oocyte complex and female fertility

About this item

Full title

Calreticulin is required for development of the cumulus oocyte complex and female fertility

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-09, Vol.5 (1), p.14254-14254, Article 14254

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Calnexin (CANX) and calreticulin (CALR) chaperones mediate nascent glycoprotein folding in the endoplasmic reticulum. Here we report that these chaperones have distinct roles in male and female fertility.
Canx
null mice are growth retarded but fertile.
Calr
null mice die during embryonic development, rendering indeterminate any effect o...

Alternative Titles

Full title

Calreticulin is required for development of the cumulus oocyte complex and female fertility

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585710

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585710

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep14254

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