Calreticulin is required for development of the cumulus oocyte complex and female fertility
Calreticulin is required for development of the cumulus oocyte complex and female fertility
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Calnexin (CANX) and calreticulin (CALR) chaperones mediate nascent glycoprotein folding in the endoplasmic reticulum. Here we report that these chaperones have distinct roles in male and female fertility.
Canx
null mice are growth retarded but fertile.
Calr
null mice die during embryonic development, rendering indeterminate any effect o...
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Full title
Calreticulin is required for development of the cumulus oocyte complex and female fertility
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585710
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4585710
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep14254