Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibro...
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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During renal fibrosis epithelial cells undergo a partial epithelial-to-mesenchymal transition that can be targeted to reverse established disease.
Kidney fibrosis is marked by an epithelial-to-mesenchymal transition (EMT) of tubular epithelial cells (TECs). Here we find that, during renal fibrosis, TECs acquire a partial EMT program during which...
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Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4587560
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4587560
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3902
