Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver
Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The source of new hepatocytes in the uninjured liver has remained an open question. By lineage tracing using the Wnt-responsive gene
Axin2
in mice, we identify a population of proliferating and self-renewing cells adjacent to the central vein in the liver lobule. These pericentral cells express the early liver progenitor marker Tbx3, are dipl...
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Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4589224
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4589224
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/nature14863
