Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Here it is shown that epithelia extrude live but not dying cells at sites of high strain, elucidating a mechanism for maintaining homeostatic cell numbers.
Crowd control in epithelia
For an epithelial-cell layer to retain its structure and provide a protective barrier, it needs to maintain a balance between the number of cells dividing and th...
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Full title
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4593481
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4593481
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10999
