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Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4595769

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

About this item

Full title

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-10, Vol.5 (1), p.14410-14410, Article 14410

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The generation of genetically-modified organisms has been revolutionized by the development of new genome editing technologies based on the use of gene-specific nucleases, such as meganucleases, ZFNs, TALENs and CRISPRs-Cas9 systems. The most rapid and cost-effective way to generate genetically-modified animals is by microinjection of the nucleic a...

Alternative Titles

Full title

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4595769

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4595769

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep14410

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