Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Myelin regeneration can occur spontaneously in demyelinating diseases such as multiple sclerosis (MS). However, the underlying mechanisms and causes of its frequent failure remain incompletely understood. Here we show, using an
in-vivo
remyelination model, that demyelinated axons are electrically active and generate
de novo
synapses wit...
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Full title
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4600759
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4600759
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9518