Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes
Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Adoptively transferred tumor-infiltrating T lymphocytes (TILs) that mediate complete regression of metastatic melanoma have been shown to recognize mutated epitopes expressed by autologous tumors. Here, in an attempt to develop a strategy for facilitating the isolation, expansion, and study of mutated antigen-specific T cells, we performed whole-ex...
Alternative Titles
Full title
Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607110
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607110
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI82416