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Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607110

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

About this item

Full title

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2015-10, Vol.125 (10), p.3981-3991

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Adoptively transferred tumor-infiltrating T lymphocytes (TILs) that mediate complete regression of metastatic melanoma have been shown to recognize mutated epitopes expressed by autologous tumors. Here, in an attempt to develop a strategy for facilitating the isolation, expansion, and study of mutated antigen-specific T cells, we performed whole-ex...

Alternative Titles

Full title

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607110

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI82416

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