Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations
Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations
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Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publisher
United States: Massachusetts Medical Society
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Contents
Somatic variants of the β-catenin gene were found in aldosterone-producing adenomas in two pregnant women. These adenomas expressed very high levels of two hormone receptors, which were presumably engaged by high levels of circulating cognate hormones.
Systematic screening detects primary aldosteronism in 5 to 10% of all patients with hypertensi...
Alternative Titles
Full title
Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4612399
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4612399
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1504869
