Hepatic progenitor cells of biliary origin with liver repopulation capacity
Hepatic progenitor cells of biliary origin with liver repopulation capacity
About this item
Full title
Author / Creator
Lu, Wei-Yu , Bird, Thomas G. , Boulter, Luke , Tsuchiya, Atsunori , Cole, Alicia M. , Hay, Trevor , Guest, Rachel V. , Wojtacha, Davina , Man, Tak Yung , Mackinnon, Alison , Ridgway, Rachel A. , Kendall, Timothy , Williams, Michael J. , Jamieson, Thomas , Raven, Alex , Hay, David C. , Iredale, John P. , Clarke, Alan R. , Sansom, Owen J. and Forbes, Stuart J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hepatocytes and cholangiocytes self-renew following liver injury. Following severe injury hepatocytes are increasingly senescent, but whether hepatic progenitor cells (HPCs) then contribute to liver regeneration is unclear. Here, we describe a mouse model where the E3 ubiquitin ligase Mdm2 is inducibly deleted in more than 98% of hepatocytes, causi...
Alternative Titles
Full title
Hepatic progenitor cells of biliary origin with liver repopulation capacity
Authors, Artists and Contributors
Author / Creator
Bird, Thomas G.
Boulter, Luke
Tsuchiya, Atsunori
Cole, Alicia M.
Hay, Trevor
Guest, Rachel V.
Wojtacha, Davina
Man, Tak Yung
Mackinnon, Alison
Ridgway, Rachel A.
Kendall, Timothy
Williams, Michael J.
Jamieson, Thomas
Raven, Alex
Hay, David C.
Iredale, John P.
Clarke, Alan R.
Sansom, Owen J.
Forbes, Stuart J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4612439
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4612439
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3203
