Np73 is capable of inducing apoptosis by co-ordinately activating several BH3-only proteins
Np73 is capable of inducing apoptosis by co-ordinately activating several BH3-only proteins
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Publisher
England: Portland Press Ltd
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Language
English
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Publisher
England: Portland Press Ltd
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Contents
Inactivation of p53 is one of the most relevant events in human cancer, since it allows transformed cells to escape their own proliferation control and leave them irresponsive to drugs that aim to damage their DNA. When p53 falls, other members of its family may become targets to attack tumoural cells. p73 has shown capacity to mediate these attack...
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Full title
Np73 is capable of inducing apoptosis by co-ordinately activating several BH3-only proteins
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4613676
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4613676
Other Identifiers
ISSN
0144-8463
E-ISSN
1573-4935
DOI
10.1042/BSR20150039
