Viruses transfer the antiviral second messenger cGAMP between cells
Viruses transfer the antiviral second messenger cGAMP between cells
About this item
Full title
Author / Creator
Bridgeman, A. , Maelfait, J. , Davenne, T. , Partridge, T. , Peng, Y. , Mayer, A. , Dong, T. , Kaever, V. , Borrow, P. and Rehwinkel, J.
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Cyclic GMP-AMP synthase (cGAS) detects cytosolic DNA during virus infection and induces an antiviral state. cGAS signals by synthesis of a second messenger, cyclic GMP-AMP (cGAMP), which activates stimulator of interferon genes (STING). We show that cGAMP is incorporated into viral particles, including lentivirus and herpesvirus virions, when these...
Alternative Titles
Full title
Viruses transfer the antiviral second messenger cGAMP between cells
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4617605
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4617605
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aab3632
