Association of activated Gαq to the tumor suppressor Fhit is enhanced by phospholipase Cβ
Association of activated Gαq to the tumor suppressor Fhit is enhanced by phospholipase Cβ
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
G proteins are known to modulate various growth signals and are implicated in the regulation of tumorigenesis. The tumor suppressor Fhit is a newly identified interaction partner of Gq proteins that typically stimulate the phospholipase C pathway. Activated Gαq subunits have been shown to interact directly with Fhit, up-regulate Fhit expression and...
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Full title
Association of activated Gαq to the tumor suppressor Fhit is enhanced by phospholipase Cβ
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4619496
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4619496
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-015-1802-z
