Chelating effect in short polymers for the design of bidentate binders of increased affinity and sel...
Chelating effect in short polymers for the design of bidentate binders of increased affinity and selectivity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The design of new strong and selective binders is a key step towards the development of new sensing devices and effective drugs. Both affinity and selectivity can be increased through chelation and here we theoretically explore the possibility of coupling two binders through a flexible linker. We prove the enhanced ability of double binders of keep...
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Full title
Chelating effect in short polymers for the design of bidentate binders of increased affinity and selectivity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4620483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4620483
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep15633
