Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
About this item
Full title
Author / Creator
Borthwick, L A , Barron, L , Hart, K M , Vannella, K M , Thompson, R W , Oland, S , Cheever, A , Sciurba, J , Ramalingam, T R , Fisher, A J and Wynn, T A
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The roles of macrophages in type 2-driven inflammation and fibrosis remain unclear. Here, using CD11b-diphtheria toxin receptor (DTR) transgenic mice and three models of interleukin 13 (IL-13)-dependent inflammation, fibrosis, and immunity, we show that CD11b
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macrophages are required for the maintenance of type 2...
Alternative Titles
Full title
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4626445
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4626445
Other Identifiers
ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/mi.2015.34
