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CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis

CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4627594

CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis

About this item

Full title

CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis

Publisher

England: BMJ Publishing Group LTD

Journal title

Gut, 2015-04, Vol.64 (4), p.544-553

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

Objective Progastrin is the incompletely cleaved precursor of gastrin that is secreted by G-cells in the gastric antrum. Both gastrin and progastrin bind to the CCK2 receptor (Cckbr or CCK2R) expressed on a subset of gastric epithelial cells. Little is known about how gastrin peptides and CCK2R regulate gastric stem cells and carcinogenesis. Interc...

Alternative Titles

Full title

CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4627594

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4627594

Other Identifiers

ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2014-307190

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