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The Hedgehog pathway: role in cell differentiation, polarity and proliferation

The Hedgehog pathway: role in cell differentiation, polarity and proliferation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4630008

The Hedgehog pathway: role in cell differentiation, polarity and proliferation

About this item

Full title

The Hedgehog pathway: role in cell differentiation, polarity and proliferation

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Archives of toxicology, 2015-02, Vol.89 (2), p.179-191

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Hedgehog
(Hh) is first described as a genetic mutation that has “spiked” phenotype in the cuticles of
Drosophila
in later 1970s. Since then, Hh signaling has been implicated in regulation of differentiation, proliferation, tissue polarity, stem cell population and carcinogenesis. The first link of Hh signaling to cancer was established thr...

Alternative Titles

Full title

The Hedgehog pathway: role in cell differentiation, polarity and proliferation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4630008

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4630008

Other Identifiers

ISSN

0340-5761

E-ISSN

1432-0738

DOI

10.1007/s00204-014-1433-1

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