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Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hy...

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4635426

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia

About this item

Full title

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-11, Vol.5 (1), p.16203, Article 16203

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Therapies to prevent severe neonatal unconjugated hyperbilirubinemia and kernicterus are phototherapy and, in unresponsive cases, exchange transfusion, which has significant morbidity and mortality risks. Neurotoxicity is caused by the fraction of unconjugated bilirubin not bound to albumin (free bilirubin, Bf). Human serum albumin (HSA) administra...

Alternative Titles

Full title

Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4635426

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4635426

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep16203

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