Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hy...
Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Therapies to prevent severe neonatal unconjugated hyperbilirubinemia and kernicterus are phototherapy and, in unresponsive cases, exchange transfusion, which has significant morbidity and mortality risks. Neurotoxicity is caused by the fraction of unconjugated bilirubin not bound to albumin (free bilirubin, Bf). Human serum albumin (HSA) administra...
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Full title
Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4635426
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4635426
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep16203