Mechanisms of retinoic acid signalling and its roles in organ and limb development
Mechanisms of retinoic acid signalling and its roles in organ and limb development
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Key Points
Retinoic acid (RA) was first implicated as a signalling molecule on the basis of its teratogenic effects on limb patterning. Studies in chick using treatment with RA or RA receptor antagonists suggested a two-signal model for limb proximodistal patterning in which a proximal RA signal opposes a distal fibroblast growth factor (FGF) si...
Alternative Titles
Full title
Mechanisms of retinoic acid signalling and its roles in organ and limb development
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4636111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4636111
Other Identifiers
ISSN
1471-0072,1471-0080
E-ISSN
1471-0080
DOI
10.1038/nrm3932
