Inhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertension
Inhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertension
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Inhibition of prostaglandin (PG) production with either nonselective or selective inhibitors of cyclooxygenase-2 (COX-2) activity can induce or exacerbate salt-sensitive hypertension. This effect has been previously attributed to inhibition of intrinsic renal COX-2 activity and subsequent increase in sodium retention by the kidney. Here, we found t...
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Full title
Inhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertension
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4639986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4639986
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI81550
