Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian canc...
Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Ovarian cancer is the most lethal gynecologic malignancy, with limited treatment options for chemoresistant disease. An important link between inflammation and peritoneal spread of ovarian cancer is NF-κB signaling. Thymoquinone (TQ) exerts multiple anti-tumorigenic cellular effects, including NF-κB inhibition. We aimed to investigate the therapeut...
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Full title
Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4640396
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4640396
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-015-0463-5
