IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signal...
IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Myeloid-derived suppressor cells (MDSCs) are immune negative regulators in the tumour microenvironment. Interleukin (IL)-11, a member of IL-6 family cytokines, functions through the unique receptor IL-11 receptor α coupled with the common signal transducer gp130. IL-11-gp130 signalling causes activation of the JAK/STAT3 pathway. IL-11 is highly upr...
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Full title
IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4642551
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4642551
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep13650
