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Alternative splicing as a biomarker and potential target for drug discovery

Alternative splicing as a biomarker and potential target for drug discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4648177

Alternative splicing as a biomarker and potential target for drug discovery

About this item

Full title

Alternative splicing as a biomarker and potential target for drug discovery

Publisher

London: Nature Publishing Group UK

Journal title

Acta pharmacologica Sinica, 2015-10, Vol.36 (10), p.1212-1218

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Alternative splicing is a key process of multi-exonic gene expression during pre-mRNA maturation. In this process, particular exons of a gene will be included within or excluded from the final matured mRNA, and the resulting transcripts generate diverse protein isoforms. Recent evidence demonstrates that approximately 95% of human genes with multip...

Alternative Titles

Full title

Alternative splicing as a biomarker and potential target for drug discovery

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4648177

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4648177

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

DOI

10.1038/aps.2015.43

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