PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma
PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma
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Author / Creator
Yu, Guanzhen , Yu, Wenlong , Jin, Guangzhi , Xu, Dongyun , Chen, Ying , Xia, Tian , Yu, Allan , Fang, Wenzheng , Zhang, Xiaoli , Li, Zhaosheng and Xie, Keping
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The therapeutic and prognostic value of the glycolytic enzymes hexokinase, phosphofructokinase, and pyruvate kinase (PK) has been implicated in a variety of cancers, while their roles in treatment of and prognosis for hilar cholangiocarcinoma (HC) remain unclear. In this study, we determined the expression of PKM2 in and its impact on biology and c...
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Full title
PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4650283
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4650283
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-015-0462-6