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Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4654749

Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

About this item

Full title

Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2015-12, Vol.130 (6), p.799-814

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

The functional dynamics and cellular sources of oxidative stress are central to understanding MS pathogenesis but remain elusive, due to the lack of appropriate detection methods. Here we employ NAD(P)H fluorescence lifetime imaging to detect functional NADPH oxidases (NOX enzymes) in vivo to identify inflammatory monocytes, activated microglia, an...

Alternative Titles

Full title

Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4654749

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4654749

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-015-1497-x

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