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The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4662256

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

About this item

Full title

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Neuroscience, 2010-12, Vol.11 (12), p.791-797

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recent evidence suggests that mutations in
LRRK2
are linked to Parkinson's disease. In this Progress article, Mark Cookson discusses how these mutations might affect LRRK2 function and its interactions with other proteins that have been implicated in Parkinson's disease, specifically α-synuclein and tau.
Parkinson's disease, like many comm...

Alternative Titles

Full title

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4662256

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4662256

Other Identifiers

ISSN

1471-003X

E-ISSN

1471-0048,1469-3178

DOI

10.1038/nrn2935

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