A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylati...
A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Regulated shedding of the ectodomain of cell membrane proteins by proteases is a common process that releases the extracellular domain from the cell and activates cell signaling. Ectodomain shedding occurs in the immediate extracellular juxtamembrane region, which is also where O-glycosylation is often found and examples of crosstalk between sheddi...
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Full title
A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4664366
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4664366
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1511175112