Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Inflammasome is an intracellular signaling complex of the innate immune system. Activation of inflammasomes promotes the secretion of interleukin 1β (IL-1β) and IL-18 and triggers pyroptosis. Caspase-1 and -11 (or -4/5 in human) in the canonical and non-canonical inflammasome pathways, respectively, are crucial for inflammasome-mediated inflammator...
Alternative Titles
Full title
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4670995
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4670995
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2015.139
