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Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for...

Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4672320

Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for migraine pathophysiology

About this item

Full title

Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for migraine pathophysiology

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-12, Vol.5 (1), p.17845-17845, Article 17845

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Migraine animal models generally mimic the onset of attacks and acute treatment processes. A guinea pig model used the application of meta-chlorophenylpiperazine (mCPP) to trigger immediate dural plasma protein extravasation (PPE) mediated by 5-HT
2B
receptors. This model has predictive value for antimigraine drugs but cannot explain the dela...

Alternative Titles

Full title

Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for migraine pathophysiology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4672320

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4672320

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep17845

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