Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for...
Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for migraine pathophysiology
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Migraine animal models generally mimic the onset of attacks and acute treatment processes. A guinea pig model used the application of meta-chlorophenylpiperazine (mCPP) to trigger immediate dural plasma protein extravasation (PPE) mediated by 5-HT
2B
receptors. This model has predictive value for antimigraine drugs but cannot explain the dela...
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Full title
Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for migraine pathophysiology
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4672320
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4672320
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep17845