Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche
About this item
Full title
Author / Creator
Lawson, Michelle A. , McDonald, Michelle M. , Kovacic, Natasa , Hua Khoo, Weng , Terry, Rachael L. , Down, Jenny , Kaplan, Warren , Paton-Hough, Julia , Fellows, Clair , Pettitt, Jessica A. , Neil Dear, T. , Van Valckenborgh, Els , Baldock, Paul A. , Rogers, Michael J. , Eaton, Colby L. , Vanderkerken, Karin , Pettit, Allison R. , Quinn, Julian M. W. , Zannettino, Andrew C. W. , Phan, Tri Giang and Croucher, Peter I.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Multiple myeloma is largely incurable, despite development of therapies that target myeloma cell-intrinsic pathways. Disease relapse is thought to originate from dormant myeloma cells, localized in specialized niches, which resist therapy and repopulate the tumour. However, little is known about the niche, and how it exerts cell-extrinsic control o...
Alternative Titles
Full title
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche
Authors, Artists and Contributors
Author / Creator
McDonald, Michelle M.
Kovacic, Natasa
Hua Khoo, Weng
Terry, Rachael L.
Down, Jenny
Kaplan, Warren
Paton-Hough, Julia
Fellows, Clair
Pettitt, Jessica A.
Neil Dear, T.
Van Valckenborgh, Els
Baldock, Paul A.
Rogers, Michael J.
Eaton, Colby L.
Vanderkerken, Karin
Pettit, Allison R.
Quinn, Julian M. W.
Zannettino, Andrew C. W.
Phan, Tri Giang
Croucher, Peter I.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4686867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4686867
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9983
