The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during agi...
The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging
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Author / Creator
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
England: John Wiley & Sons, Inc
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Contents
Summary
Sarcopenia, the loss of skeletal muscle mass and function during aging, is a major contributor to disability and frailty in the elderly. Previous studies found a protective effect of reduced histone deacetylase activity in models of neurogenic muscle atrophy. Because loss of muscle mass during aging is associated with loss of motor neuro...
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Full title
The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4693467
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4693467
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12387