Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell via...
Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability
About this item
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Author / Creator
Cui, X , Zhang, L , Magli, A R , Catera, R , Yan, X-J , Griffin, D O , Rothstein, T L , Barrientos, J , Kolitz, J E , Allen, S L , Rai, K R , Chiorazzi, N and Chu, C C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The degree of chronic lymphocytic leukemia (CLL) B-cell antigen receptor (BCR) binding to myosin-exposed apoptotic cells (MEACs) correlates with worse patient outcomes, suggesting a link to disease activity. Therefore, we studied MEAC formation and the effects of MEAC binding on CLL cells. In cell line studies, both intrinsic (spontaneous or campto...
Alternative Titles
Full title
Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703467
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703467
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2015.204
