Transcriptional elongation requires DNA break-induced signalling
Transcriptional elongation requires DNA break-induced signalling
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
We have previously shown that RNA polymerase II (Pol II) pause release and transcriptional elongation involve phosphorylation of the factor TRIM28 by the DNA damage response (DDR) kinases ATM and DNA-PK. Here we report a significant role for DNA breaks and DDR signalling in the mechanisms of transcriptional elongation in stimulus-inducible genes in...
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Transcriptional elongation requires DNA break-induced signalling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703865
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703865
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10191
