Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression
Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In primates, puberty is unleashed by increased GnRH release from the hypothalamus following an interval of juvenile quiescence. GWAS implicates
Zinc finger
(
ZNF
) genes in timing human puberty. Here we show that hypothalamic expression of several
ZNF
s decreased in agonadal male monkeys in association with the pubertal reactivati...
Alternative Titles
Full title
Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703871
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703871
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10195