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Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703871

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

About this item

Full title

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-12, Vol.6 (1), p.10195-10195, Article 10195

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In primates, puberty is unleashed by increased GnRH release from the hypothalamus following an interval of juvenile quiescence. GWAS implicates
Zinc finger
(
ZNF
) genes in timing human puberty. Here we show that hypothalamic expression of several
ZNF
s decreased in agonadal male monkeys in association with the pubertal reactivati...

Alternative Titles

Full title

Epigenetic regulation of puberty via Zinc finger protein-mediated transcriptional repression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4703871

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms10195

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